Guidance for the use of genetically modified mosquitoes

This Guidance document provides direction for the development, testing and deployment of gene drive technology for the control of arthropodborne diseases. It will be a reference framework for developers, promoters and users of the technology. Its use provides a roadmap for safeguarding human and ethical values, addressing safety concerns, enhancing quality and consistency of procedures and proposing ways for appropriate governance. The guidance is based on the latest research evidence on characteristics of gene drive organisms, best practices for evaluating genetically modified mosquitoes (GMMs) with a particular focus on the gene drive technology, and its potential risks and benefits. In addition to this document, the regulator and all other actors are expected to use all the other relevant guidelines for further details.