Last Updated: 01/08/2024
Which Plasmodium falciparum virulence antigens elicit immunity associated with protection from severe malaria?
Objectives
This project will identify the deadly parasite binding proteins, find out whether antibodies to them are protective, investigate how they bind and determine how common the deadly parasites are.
Principal Institution
Principal Investigators / Focal Persons
Rationale and Abstract
Malaria parasites kill by binding infected cells to blood vessel walls. The binding proteins appear more similar to each other in deadly parasites than in parasites that don’t cause severe malaria. The knowledge obtained from the research will help to develop therapies to block binding and to assess the viability of vaccines.
External reference
Thematic Categories
Date
Jan 2024 — Dec 2026
Total Project Funding
$601,650
Funding Details
National Health and Medical Research Council (NHMRC) Australia, Australia
Grant ID: 2029583
AUD 890,588
Project Site
