Last Updated: 05/07/2024

West African Network for TB, AIDS and Malaria (WANETAM I)

Objectives

The targeted general objectives of WANETAM 1 were:

  1. To promote capacity building & technology transfer to prepare West African institutes for the successful conduct of clinical trials.
  2. To create a network for sub-regional scientific collaborations

Work package(WP)  2 of this network was in charge of the malaria research. This work package aims at increasing capacities for the evaluation of new interventions/, treatments and vaccines able to further reduce and interrupt malaria transmission. Led by MRC Unit The Gambia at LSHTM, the activities of this work package are aimed at achieving the following objectives:

  1.  To build capacities for the evaluation of new community-based interventions aimed at interrupting malaria transmission in West Africa
  2.  To build capacities for the evaluation of the efficacy of new insecticides and the monitoring of insecticide resistance
  3. To build capacities to determine safety and efficacy of new treatments and vaccines
  4. To set up a Controlled Human Malaria Infection (CHMI) model in The Gambia, with the aim of conducting early phase trials on new treatments and vaccines.
Rationale and Abstract

WANETAM was established in 2009 through the support of EDCTP. The first phase of the network’s operation was implemented from 2009 to 2014. This included 14 institutions from seven countries. The network was further strengthened within the last two years by the contribution of EU member-states (Belgium and UK) initiated research project (WANETAM-plus), which ensured the inclusion of other African institutions, such as Benin.

At the end of WANETAM 1, the network registered major achievements including:

  1. Created a collaborative research network of scientists from Anglophone, Francophone and Lusophone countries in West Africa.
  2. Supported short-term trainings that built both laboratory and clinical skills in the field of HIV, Malaria, and TB as well as in cross cutting disciplines, in view to support proficiency in clinical research including TB and HIV molecular diagnostic techniques, high-throughput molecular research techniques, immunological flow cytometry and multiplex assays, GCLP and GCP, Laboratory Equipment Maintenance skills, Ethics training, community support and engagement.
  3. Facilitated hands-on surveillance training on multi-drug resistance, establishment of normal values of haematological and biochemical parameters in African subjects, and antimalarial drug resistance monitoring including molecular markers.
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