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Last Updated: 24/03/2023

Understanding and targeting coenzyme A biosynthesis and utilisation in Plasmodium falciparum

Objectives

To understand how the human malaria parasite P. falciparum metabolises vitamin B5, an essential molecule for the parasite. 

Principal Investigators / Focal Persons

Kevin Saliba

Rationale and Abstract

This grant describes a series of studies designed to understand how the human malaria parasite P. falciparum metabolises vitamin B5, an essential molecule for the parasite. We will also carry out experiments to determine how a new series of vitamin B5 analogues we have developed kill the parasite and aim to start developing these compounds into new and much needed antimalarial medications.

Thematic Categories

Enabling Technologies & Assays

Date

Jan 2017 — Dec 2019

Total Project Funding

$409,285

Project Site

Australia

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