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Last Updated: 02/08/2024

Targeting the host lipid environment to disrupt malaria transmission

Objectives

This project aims to characterise host molecules (in particular lipids) that are crucial for the transition of malaria parasites from one host to another.

Principal Investigators / Focal Persons

Alexander Maier
Todd Mitchell

Partner Investigators

Benjamin Mordmüller

Rationale and Abstract

Malaria parasites encounter different environments upon their transition from human to the mosquito host. This project expects to generate new knowledge on physiological changes that are triggered by particular differences in micronutrient abundance that allow the parasites to survive in the new host. Anticipated outcomes include the identification of new intervention strategies and improved transmission model systems for vector-borne diseases. This gained knowledge could provide benefits to future biomedical applications by informing diagnostics or treatment of lipid associated diseases.

Thematic Categories

Basic Science

Date

Jan 2024 — Dec 2026

Total Project Funding

$465,236

Funding Details
Australian Research Council (ARC), Australia

Grant ID: DP240100929
AUD 688,670
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