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Last Updated: 27/10/2022

A study to determine if a new Malaria vaccine is safe and induces immunity among Kenyan adults, young children and infants.

Objectives

To evaluate the safety and immunogenicity of different doses of a candidate Malaria vaccine; adjuvanted R21(R21/MM) in adults, young children and infants in Kilifi, Kenya.

Principal Investigators / Focal Persons

Adrian VS Hill

Rationale and Abstract

This is a clinical trial to evaluate the safety and immunogenicity of R21/MM in healthy Kenyan participants from the different age groups.

The study includes three age groups:

Group 1: healthy adults (18-45 years)

Group 2: young children (aged 1-5 years)

Group 3: infants (aged 5- <12 months of age)

Each group will receive 3 vaccine doses which will be 4-weeks apart.

NCT number: NCT03580824

Study Design

Study type: Interventional

Enrollment: 91 participants

Allocation: Non-Randomized

Intervention model: Parallel Assignment

Masking: None (Open Label)

Primary purpose: Treatment

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