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Last Updated: 04/07/2024

Screening for transmission blocking drugs

Objectives

This project aims to develop novel antimalarial compounds targeting gametocytes, the sexual stages of the Plasmodium falciparum parasite responsible for severe human malaria.

Principal Investigators / Focal Persons

Michael Delves

Rationale and Abstract

This initiative focuses on screening new antimalarial compounds for “transmission-blocking” activity, crucial for interrupting the cycle of infection and aiding malaria elimination efforts.

Utilizing a groundbreaking high throughput screening assay, the lab can evaluate the effectiveness of antimalarial drugs on both male and female gametocytes simultaneously, a vital step as each sex responds differently to treatment.

Date

Jan 2022 — Dec 2022

Total Project Funding

$130,000

Funding Details
Medicines for Malaria Venture (MMV), Switzerland

$130,000
Grant ID: PO22/00164
GBP 86,667
Project Site

United Kingdom

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