Last Updated: 18/08/2025

Resistance to artemisinin, the first-line drug that first appeared in Africa Malaria: Elucidation of the epidemic mechanism

Objectives

*Original title and abstract were machine translated from Japanese.

To elucidate the epidemic mechanism of artemisinin resistance and to establish a scientific basis for resistance containment.

Principal Institution

Juntendo University, Japan

Principal Investigators / Focal Persons

Toshihiro Mita

Partner Institutions

University of Tokyo, Japan

Partner Investigators

Jun Ohashi
Makoto Hirai

Rationale and Abstract

Malaria is one of the world’s three largest mosquito-borne infectious diseases. Artemisinin derivatives are the first-line drug for malaria, but applicants have confirmed that resistance has also emerged in Africa and has increased rapidly over the years. But it is unclear why that is happening. The results will enable the containment of resistance based on scientific evidence.

Date

Apr 2022 — Mar 2026

Total Project Funding

$145,484

Funding Details
Project Site

Japan

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