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Last Updated: 02/08/2024
Research and development that contributes to countermeasures against parasitic diseases prevalent in Japan and imported parasitic diseases
Objectives
*Original title and text were machine translated from Japanese.
This research project will examine the influence of candidate proteins on the pathogenesis of cerebral malaria, and investigate the pathogenesis of cerebral malaria. The aim is not only to elucidate this, but also to discover biomarkers that are useful for early diagnosis.
The purpose of this research project is to examine the involvement of allergies in gastric anisakiasis, and clarify the pathology of anisakiasis as an allergy by comparing humans who develop anisakiasis with those who do not. This research group has established a mouse model of gastric anisakiasis, and will investigate mouse models in addition to humans. Furthermore, we will also examine the composition of the resident bacterial flora and metabolites in the stomach contents, which are thought to be related to the development of allergies. Using blood samples from malaria patients in Uganda, a protein has been found that specifically increases in severe malaria, especially cerebral malaria.
Apr 2023 — Mar 2026
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