A quasi-experimental study to assess the effectiveness of Malaria Camps as part of the Odisha State malaria elimination drive (India ICEMR)

Study Type: Interventional (Clinical Trial)
Allocation: Non-Randomized
Intervention Model: Parallel Assignment (Quasi-experimental cluster-assigned stepped-wedge study)
Masking: None (Open Label)
Estimated Enrollment:   2700 participants

Malaria Camps combine focused screening and treatment with intensified vector control. Malaria screenings are conducted with a Rapid Diagnostic Test (RDT) that targets both P.f. and P.v. infections, and RDT-positive subjects identified during the visits are told to seek the standard of care as per Govt. of India guidelines, through their local health worker (called an ASHA) or public health center (PHC).

In particular, the program includes one round of testing and treatment for the whole village population before the monsoon season, followed by one or two rounds of screening and treatment of fever cases only during / after the monsoon season.

In the first year, villages will be assigned across three study arms:

• Arm 1: receive new MCs
• Arm 2: control with no MCs but with standard malaria control
• Arm 3: villages already in receipt of MCs prior to study initiation (to assess longer term effects)

In the second year, both Arm 1 and Arm 2 villages will receive the MC intervention (i.e. non-randomized stepped-wedge design).

MC effectiveness will be evaluated from epidemiologic surveys and PCR detection of malaria prevalence. Factors affecting the implementation of the intervention will be assessed by qualitative interviews, focus group discussions and cost-effectiveness evaluations.

ClinicalTrials.gov - Project details

Combination of Interventions
Drug-based Strategies
Health Systems & Op. Research
Impact of Interventions

Aug 2019 — Sep 2021

$1.08M

India

Center for the study of complex malaria in India (India ICEMR)

Mass Test and Treat (MTaT) strategies