Last Updated: 25/03/2025

Predicting the impact of antimalarial resistance in West African parasites

Objectives

In this project African resistance mutations will be introduced into culture-adapted parasites from circulating infections in Ghana (West Africa). This will enable predictions to be made about how these specific mutations will affect drug treatment regimen in West Africa.

Principal Institution

Burnet Institute, Australia

Principal Investigators / Focal Persons

Hayley Bullen

Rationale and Abstract

Malaria causes significant morbidity and mortality. The majority of the disease burden is in Africa. Resistance to the frontline antimalarial artemisinin has developed in Southeast Asia and is now present in East but not West Africa. 

Date

Jan 2025 — Dec 2027

Total Project Funding

$865,800

Project Site

Ghana

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