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Last Updated: 09/10/2023

PMC pilot implementation in DRC

Objectives

The aim of this project is to assess the operational feasibility, acceptability and cost of perennial malaria chemoprevention (PMC) and effectiveness in reducing clinical malaria in children under the age of two. 
Specific Objectives include:  

  1. Through a co-design process, develop the optimal model of PMC implementation in the DRC, including number of touchpoints, timing and delivery channels of SP doses;
  2. Estimate PMC coverage in eligible children 6-23 months of age in the intervention areas; 
  3. Estimate the association between severe malaria and receipt of the last eligible dose of PMC in children 6-23 months of age; 
  4. Assess changes in the incidence of clinical malaria in children under two years of age; 
  5. Assess the operational feasibility, knowledge, ease of use and acceptability of PMC by health care providers; 
  6. To assess the operational feasibility, knowledge, and acceptability of PMC by community members; and 
  7. To estimate the cost of the intervention implementation and its cost-effectiveness. 
     
Principal Institution

PATH, United States

Principal Investigators / Focal Persons

Henry Ntuku

Rationale and Abstract

Since the 2010 WHO recommendations on perennial malaria chemoprevention (PMC) formerly known as intermittent preventive treatment in infants (IPTi), many high-burden countries, including the DRC, have expressed interest in introducing and scaling up PMC. However, lack of funding and local evidence on operational feasibility have been among the main obstacles to the introduction and implementation of PMC. The updated 2022 WHO recommendations provide more flexibility to countries in using existing data to develop the optimal PMC model including number of touchpoints, timing and delivery channels of SP. With funding from Givewell, PATH is providing technical support to the National malaria control program (NMCP) of the DRC for the introduction of PMC into the routine malaria interventions.

Thematic Categories

Response Strategies

Date

Dec 2022 — Dec 2024

Total Project Funding

$6.23M

Funding Details
Project Site

Dem. Rep. of Congo

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