Last Updated: 23/09/2020
Modelling the potential of focal screening and treatment as elimination strategy for Plasmodium falciparum malaria in the Peruvian Amazon Region
Objectives
The objective of this study was to use a relatively straightforward mathematical model to assess the long term impact of Focal Screening and Treatment (FSAT) on the P. falciparum malaria transmission intensity in a low endemic area of the Peruvian Amazon Region.
A baseline model was developed to simulate a scenario with seasonal malaria transmission and the effect of passive case detection and treatment of symptomatic infections on the P. falciparum malaria transmission in a low endemic area of the Peruvian Amazon. The model was then adjusted to simulate intervention scenarios for predicting the long term additional impact of FSAT on P. falciparum malaria prevalence and incidence. Model parameterization was done using data from a cohort study in a rural Amazonian community as well as published transmission parameters from previous studies in similar areas.
The effect of FSAT timing and frequency, using either microscopy or a supposed field PCR, was assessed on both predicted incidence and prevalence rates.
Jan 2011 — Jun 2015
