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Last Updated: 14/05/2024
Medicinal chemistry progression of hits identified from the MMV pathogen box for malaria and tuberculosis
Objectives
This project seeks to continue medicinal chemistry efforts on a chemical class identified from the medicines for malaria venture (MMV) Pathogen box to develop an early lead with in vivo antitubercular/antimalarial activity as a proof-of-concept.
The emergence of drug resistance has rendered most clinically used drugs ineffective. There is, therefore, the need to discover new, safe, effective and novel chemo types with new modes of action. This project seeks to continue medicinal chemistry efforts on a chemical class identified from the MMV Pathogen box to develop an early lead with in vivo antitubercular/antimalarial activity as a proof-of-concept
May 2019