Last Updated: 18/06/2024

Manipulating antibody production to maximise memory in vaccine responses

Objectives

To study and manipulate antibody production to maximise memory in vaccine responses.

Principal Institution

Monash University (MON), Australia

Principal Investigators / Focal Persons

Isaak Quast

Rationale and Abstract

The immune system provides protection from germs. The secretion of germ-specific proteins (antibodies) is an integral component of this defence and the basis of virtually all vaccines. Pandemics of Influenza and SARS-CoV-2 and failure to develop vaccines against HIV and Malaria remind us that our strategies need urgent improvement. Increasing the understanding of how human body defends itself by specifically targeting foreign structures will reveal avenues for successful, rational vaccine development.

Thematic Categories

Vaccines (Immune Correlates)

Date

Jan 2021 — Dec 2024

Total Project Funding

$794,419

Project Site

Australia

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