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Last Updated: 19/06/2024

Malaria volunteer infection studies for the advancement of antimalarial therapeutics

Objectives

To characterise the Pharmacokinetic/Pharmacodynamic (PK/PD) profile of existing antimalarials to optimise dose selection, evaluate the transmission blocking activity of new and existing antimalarials, and evaluate strategies to boost antimalarial immunity.

Principal Investigators / Focal Persons

Bridget Barber

Rationale and Abstract

Malaria volunteer infection studies will be conducted to advance the development of antimalarial therapeutics. This will include studies to characterise the PK/PD profile of existing antimalarials to optimise dose selection, evaluate the transmission blocking activity of new and existing antimalarials, and evaluate strategies to boost antimalarial immunity. These studies will inform antimalarial treatment strategies worldwide.

Thematic Categories

Product Development

Date

Oct 2022

Total Project Funding

$977,871

Project Site

Australia

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