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Last Updated: 06/02/2024

Long COVID research

Objectives

The aims of this projects are
1) to compare the prevalence of, and risk factors for, malaria infection among individuals with and without previous SARS-CoV-2 infection
2) to compare the prevalence of fever and describe healthcare pathways for its management among individuals with and without previous SARS-CoV-2 infection
3) to determine the prevalence and predictors, and describe the clinical spectrum, of long-term complications of COVID-19 among individuals with previous SARS-CoV-2 infection, as well as its risk factors
4) to describe the association between previous malaria exposure and the development of long-term complications of COVID-19 among individuals with previous SARS-CoV-2 infection
5) to describe the relationship between previous malaria exposure and risk of SARS-CoV-2 infection.

Principal Institution

Malaria Consortium, United Kingdom

Rationale and Abstract

This study is taking place in Ethiopia and Uganda. It uses both qualitative and quantitative approaches and a case control study design to explore the relationship between past SARS-CoV-2 infection and malaria risk. A sample size of 2400 cases and 2400 controls (n=4800) will be enrolled from both countries. In Ethiopia, the researchers will conduct the study in three hospitals: one in Addis Ababa and two in Hawassa. In Uganda, the study will be conducted in different COVID-19 treatment centres across the country. The study population includes individuals across all age groups, both male and female, with previous SARS-CoV-2 infection (who were either hospitalised or not hospitalised during acute illness) as well as those without. Three overarching questions underpin this study: How do people with long term complications of COVID-19 (including those who were never hospitalised) experience the development, course and resolution of the illness over time? What services have they accessed (or tried to access), and what was their experience of those services? What are their ideas for improving the management of their condition and the design and delivery of services?

Project Outputs

Project brief

Date

Mar 2021 — Mar 2024

Total Project Funding

$854,999

Project Site

Ethiopia
Uganda

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