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Last Updated: 19/06/2024
Limited IFN-gamma blockade enhances development of memory CD4+ T cells during malaria
Objectives
*Original title and abstract were machine translated from Japanese.
To investigate whether the timed neutralization of IFNγ up to the acute phase inhibits its differentiation suppression and enhances the formation of immunological memory CD4 + T cells.
Principal Institution
Principal Investigators / Focal Persons
Rationale and Abstract
During the acute phase of Plasmodium malaria infection, IFNγ produced from Th1 cells and the like suppresses the determination of activation protozoan-specific CD4 + T cells to differentiate into memory cells.
External reference
Thematic Categories
Date
Apr 2022 — Mar 2025
Total Project Funding
$35,000
Funding Details
Project Site
Related Resources
