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Last Updated: 15/07/2024
Intermittent Preventative Treatment in Infants
Objectives
The overall aim is to reach more children, more frequently, in the first years of life to reduce malaria in young children and infants and save lives.
Specific objectives are:
- to facilitate a country-led process with each country’s Ministry of Health to co-design IPTi+ models specific to each setting. The four implementation countries – Benin, Cameroon, Côte d’Ivoire, and Mozambique – represent diverse health systems and differ in the level of malaria transmission and in the implementation of other malaria interventions; and
- to generate evidence to inform country and global-level adoption and scale-up of IPTi+, evaluating the impact, process, and cost-effectiveness.
London School of Hygiene and Tropical Medicine (LSHTM), United Kingdom
IPTi+ targets a crucial population. Children under the age of five years are among the most vulnerable to malaria, accounting for nearly 70% of the estimated 409,000 malaria deaths globally in 2019. More than half of these deaths (54%) are estimated to have occurred in children below two years of age.
Intermittent Preventive Treatment of malaria in infants (IPTi) using the combination anti-malaria medication sulfadoxine-pyrimethamine (SP) is a safe, affordable, and effective intervention shown to reduce rates of malaria and anaemia in children under one year of age by 30% and 21% respectively. The World Health Organization (WHO) recommended IPTi for use in 2010, yet the intervention has only been implemented in Sierra Leone to date, and has not been widely adopted in Africa.
Drug-based Strategies
Financing & Economics
Impact of Interventions
Aug 2021 — Jul 2025
$11.89M
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