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Last Updated: 10/05/2023
An innovative pipeline to establish the complete Plasmodium vivax life-cycle in the laboratory – VICTOR
Objectives
The main objective of this project is to join forces and expertise for implementing an innovative pipeline establishing the complete Plasmodium vivax life-cycle in the laboratory, independent of transmission seasons and heavy logistic constraints for establishing connections with collection sites located in malaria endemic settings.
Institut Pasteur of Madagascar (IPM), Madagascar
Addis Ababa University, Ethiopia
Research on P. vivax is greatly lagging behind P. falciparum mainly due to the absence of an efficient laboratory cultivation system on one hand. On the other hand most of the current investigations are compartmentalized, focusing specifically on either individual P. vivax stage (blood stage, liver stage, mosquito stage). This platform will provide the today major missing piece of the puzzle to enlarge the general knowledge on P. vivax biology and pave the way for boosting research on P. vivax and promoting the development of potential innovative novel interventions such as new therapeutics and vaccines.
Sep 2021 — Sep 2023
$366,748
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