Last Updated: 02/08/2024
Identification of drug resistance gene from multiple-resistant malaria parasite
Objectives
*Original title and text were machine translated from Japanese.
This study will identify artemisinin and lumefantrine resistance genes from the acquired multidrug-resistant protozoa using a uniquely developed method.
Currently, malaria treatment is a combination therapy using artemisin and other antimalarial drugs (Artemisinin Combination Therapy, ACT) is the first choice. However, in recent years, resistance to these drugs has spread on a global scale, and there is a strong concern that the therapeutic efficacy will decline. The results of this research will not only lead to an understanding of the molecular basis of the resistance acquisition mechanism of protozoa, but alsoACTIt will provide molecular markers to monitor the spread of resistance to the drugs used, and will greatly contribute to the promotion of malaria control.
Apr 2023 — Mar 2026
$140,642
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