Last Updated: 09/03/2023

Host targeted adjunctive therapies to boost antimalarial immunity

Objectives

To investigate the ability of a repurposed drug to prevent the development of disruptive immune responses during malaria in humans. 

Principal Investigators / Focal Persons

Michelle Boyle

Rationale and Abstract

Malaria caused 200 million cases and 400000 deaths in 2018. One problem in developing new control strategies for malaria is that following a malaria infection, individuals develop disruptive immune responses that block vaccines. Our project investigates the ability of a repurposed drug to prevent the development of disruptive immune responses during malaria in humans. Results of our studies will inform the development of new malaria control tools.

Thematic Categories

Drug-based Strategies

Date

Jan 2021 — Dec 2022

Total Project Funding

$1.52M

Project Site

Australia

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