Last Updated: 16/11/2018
Highly-sensitive RDT evaluation study in Mozambique
Objectives
The overall objective of this project is to evaluate the level of highly-sensitive RDT detection of additional infections compared to RDT in post-MDA areas (Magude District, Xinavane Area) and no interventions (Manhica District).
Additional specific objectives:
- To assess the distribution of parasitemia in three low prevalence areas
- To evaluate the highly-sensitive RDT performance by sensitivity, specificity, NPV and PPV against RDT, microscopy, and PCR results
- To assess the presence of hrp2/3 deletion parasites (done until 2016)
Principal Institution
Principal Investigators / Focal Persons
Partner Institutions
Rationale and Abstract
- Outcomes:
- (Individual level) Assess the distribution of parasitemia in three low prevalence areas; Diagnostic accuracy (sensitivity, specificity, NPV and PPV); Presence of hrp2/3 deletion parasites.
- (Community level) Evaluate the level of highly-sensitive RDT detection of additional infections in post-MDA areas and no intervention areas.
- Gold standard: qPCR
- Population selection criteria: Simple random sampling of children and adults
- Sample size: n=4396 (4149 high transmission area, 247 low transmission)
Study Design
Population cross-sectional survey
Thematic Categories
Date
Apr 2017 — Jun 2017
Funding Details
Project Site
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