Last Updated: 01/10/2025

Functional analysis of the most degraded chloroplasts possessed by the shellfish parasite Perkinsus

Objectives

This study aims to understand the universal physiological significance of apicoplasts and the path and principles of functional degeneration of this organelle due to parasitic adaptation by clarifying the metabolites synthesized in Perkinsus chloroplasts.

 

Principal Investigators / Focal Persons

Hirokazu Sakamoto

Rationale and Abstract

Apicomplexa protozoa, such as malaria parasites and Toxoplasma, possess apicoplasts, organelles of chloroplast origin, within their cells. While apicoplasts are essential for the survival of protozoa, their universal physiological significance is not fully understood. This study focuses on the most degenerate chloroplasts of the shellfish parasitic protozoan Perkinsus, a closely related species to Apicomplexa, which has even lost its unique genome, and aims to elucidate the metabolic pathways remaining there. 

Date

Mar 2021 — Mar 2025

Total Project Funding

$31,143

Funding Details
Project Site

Japan

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