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Last Updated: 09/10/2023
Evaluation of the interpretation and reporting of malaria RDT results with PMI Insights
Objectives
This project under PMI Insights will accomplish following objectives:
- Measure agreement between HCW and panel RDT results in Benin, Côte d’Ivoire, Nigeria and Uganda;
- Measure the statistical association between key characteristics of HCWs, RDT guidelines, health systems, malaria epidemiology and patient demographics and type of agreement/disagreement between the HCW and panel RDT results;
- Understand how characteristics of HCWs, RDT guidelines, health systems, malaria epidemiology and patient demographics affect the ability of HCWs to accurately implement, interpret, use, record and report RDT results;
- Assess the fidelity of data entry from health facility registers to the health management information system (HMIS);
- Determine the degree of over- and under- treatment for malaria and statistical associations with characteristics of HCWs, RDT guidelines, health systems, malaria epidemiology and patient demographics;
- Determine whether there is an observer impact of the study on monthly number of RDT positive results and TPRs;
- Determine the frequency of RDT anomalies that affect visual interpretation of results;
- Calculate the accuracy of HealthPulse (Audere, Seattle, WA), a smartphone-based application that uses artificial intelligence to interpret RDT results, compared to the panel RDT results after training on a random selection of RDT photographs; and
- Determine the durability of RDT results over time by comparing agreement of RDT results read at one week and one month after administration with the initial read.
PMI Insights is conducting operations research in Benin, Cote d’Ivoire, Nigeria, and Uganda to measure the degree of agreement between RDT results as recorded in health facility registers and results determined by an independent, objective panel that will independently review high-quality photographs of the RDTs taken through a phone-based application. The study, led by local research partners in each of the four focus countries, also seeks to identify factors at the level of the individual patient, healthcare worker, facility, transmission season, and transmission setting that affect the type of agreement or disagreement between healthcare worker and panel RDT results.
Nov 2022 — Dec 2025
$3M