Elucidation of the mechanism of malaria aggravation focusing on stress control and development of new treatment methods

Objectives

*Original title and abstract were machine translated from Japanese.

This study aims at elucidation of the mechanism of malaria aggravation and development of new treatment methods by focusing on stress control such as oxidative stress and endoplasmic reticulum stress.

Principal Institution

Saitama Medical University, Japan

Principal Investigators / Focal Persons

Takashi Imai

Rationale and Abstract

Malaria is the largest infectious disease in the world. We have been conducting research and development on immunity, pathology, diagnosis and vaccines for malaria. In severe malaria, even if the protozoan is treated with antimalaria drugs, many pediatric patients die due to complications such as brain malaria and lung damage, so it is necessary to elucidate the pathology and improve the treatment method.

External reference

Project details

Thematic Categories

Basic Science

Date

Apr 2022 — Mar 2025

Total Project Funding

$35,000

Funding Details

Japan Society for the Promotion of Science (JSPS), Japan

Grant ID: 22K06582

JPY 4.16M