Effectiveness of forest-based malaria control interventions in large forests of Cambodia

Objectives

The main goal is to eliminate malaria in the study forest using a combination of MSAT (Mass Screening and Treatment), PCD (Passive Case Detection), and RACD (Reactive Case Detection).

The key activities of the project include:
• Mapping of hotspots using GIS.
• Baseline and end-line entomology surveys.
• Quarterly MSAT: Highly-sensitive RDT testing followed by treatment of positive P.f cases using ASMQ and single low dose Primaquine, together with vector control kit.
• PCD through Forest Malaria Workers (FMWs) and health centers using standard RDT. Positive P.f cases will be given ASMQ and single low dose Primaquine, together with vector control kit.
• Follow up and conduct RACD: FSAT (Focal Screening and Treatment) with HS-RDT or fMDA (Focal Mass Drug Administration) to the contacts of positive cases identified through PCD. Those who are positive for P.f will be provided with ASMQ and single low dose Primaquine, together with vector control kit that will include LLIHNs and instructions to prevent malaria in forest.
• Surveys to measure malaria prevalence (dry blood spot collection and analysis through PCR).