Last Updated: 01/08/2024
Defining new mechanisms of action and resistance for the malaria drug proguanil
Objectives
This project addresses the need to understand how existing malaria drugs work by investigating the mode of action and potential resistance mechanisms of the antimalarial drug proguanil.
Principal Institution
Principal Investigators / Focal Persons
Rationale and Abstract
Malaria causes >200 million clinical cases and >600,000 deaths annually. There is no broadly effective malaria vaccine and drug resistance is a significant global problem. Thus, it is essential that current drugs are used effectively to limit parasite resistance development and to ensure their continued use.
External reference
Thematic Categories
Date
Jan 2024 — Mar 2027
Total Project Funding
$561,608
Funding Details
National Health and Medical Research Council (NHMRC) Australia, Australia
Grant ID: 2029164
AUD 831,316
Project Site
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