DEEP DIVE

Targeted Test and Treat (TTaT) strategies

Creation date:

11/11/2020

Last modified date:

21/03/2024

This is an active Deep Dive and we welcome your contributions! If you are currently involved or planning research activities on Targeted Test and Treat (TTaT) strategies please contact MESA (mesa@isglobal.org) or add your project to the database.

——

Targeted Test and Treat (TTaT) strategies for malaria are defined by WHO as testing a sub-population at high risk of infection with a parasitologic test, and treating confirmed malaria cases to reduce transmission (risk factors include demographic, occupational and exposure characteristics).

In malaria endemic countries, there are population groups whose occupational exposures in specific work sites –such as forests, mining areas, plantations and military encampments– or outdoor leisure activities put them at higher risk of malaria infection. However, there is still very limited evidence to show whether providing these high-risk groups full treatment courses of antimalarials through TTaT interventions would help reduce transmission.

A variant of the TTaT strategy is testing and treating migrants and visitors passing through international or national ports of entry. Testing for malaria at ports of entry to prevent importation of malaria into the country is actively promoted in various subregional elimination strategies, and yet there has been no review of evidence to demonstrate the appropriateness of this approach, nor has there been a review of the acceptability or feasibility of this strategy that could guide implementation considerations.

The WHO Global Malaria Programme is currently developing new Guidelines for Malaria Elimination to provide policy advice to countries. Evidence-based recommendations on the use and implementation of TTaT interventions will be included in these guidelines.

With the aim of facilitating the work of the Malaria Elimination Guidelines Development Group, this deep dive compiles the landscape of recent and ongoing research in malaria TTaT strategies and provides an overview of the projects’ main characteristics.

MESA Track
Total
projects

0 active
MESA Track
Total funding
amount

MESA Track
Project
sites

Research Area

Total Projects

Project Timeline

Research Area

Total Projects

    Project Timeline

    Research Area

    Total Projects

      Project Timeline

      FILTERS

      Reset filters
      Principal Institutions
      Projects|Funding



      Principal Investigators

        Funding Sources

        Principal Institutions

        Principal Investigators

        Funding Sources

        Principal Institutions


        Latest projects