Perennial Malaria Chemoprevention (PMC) – [formerly IPTi]

This is an active Deep Dive and we welcome your contributions! If you are currently involved or planning research activities on Perennial Malaria Chemoprevention (PMC) – formerly called Intermittent Preventive Treatment in infants (IPTi) – please contact MESA (mesa@isglobal.org) or add your project to the database.

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A WHO Technical Consultation to Review the Role of Drugs in Malaria Prevention for People Living in Endemic Settings took place on October 16 – 17, 2019 [ref]. The meeting discussed malaria chemoprevention including SMC, IPTi (PMC) and IPTp strategies, with the aim to review the state-of-the-art in the use of chemoprevention to reduce deaths, morbidity and anaemia from malaria, and to reduce malaria transmission, and provide guidance to WHO on priority investments in malaria chemoprevention for people living in endemic settings.

To facilitate the meeting’s work, MESA compiled a landscape of research in PMC, defined as the administration of a full therapeutic course of antimalarial medicine at predefined intervals, to prevent illness in children in moderate to high perennial malaria transmission settings, regardless of the malaria infection status.  

Further information on this topic is available in the WHO MagicApp.