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Last Updated: 01/08/2024

Change of G6PD activity in the course of malaria

Objectives

This project will test whether G6PD levels increase during a malaria attack, rendering treatment much safer than what is assumed to date.

Principal Investigators / Focal Persons

Benedikt Ley

Rationale and Abstract

Malaria is a serious and potentially deadly disease. Following a first symptomatic phase, some malaria species develop asymptomatic forms that cause a second symptomatic phase weeks to months after the first episode. The drugs currently used to treat this malaria species can cause severe side effects in people with low activities of a particular enzyme (G6PD).

Thematic Categories

Basic Science

Date

Jan 2024 — Feb 2027

Total Project Funding

$871,583

Project Site

Australia

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