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Last Updated: 29/07/2024

Broad One Health Endectocide Based Malaria Intervention for Africa_Tanzania site

Objectives

The purpose of this project is to confirm the attractiveness of HBMPP to dominant malaria vectors in Africa using Marathon Tunnel, and natural conditions in the field. Also, the project will confirm why malaria vectors are attracted to malaria patients in endemic settings using the quantity of volatiles exhaled or emitted by the individuals.

Principal Investigators / Focal Persons

Issa Lyimo

Rationale and Abstract

Malaria parasites circulating in human blood and transmitted to another individual through mosquito bites. These parasites especially gametocytes circulating in the blood generates metabolites (GCM), HMBPP, which acts as both phagostimulant (enhancing mosquito feeding), and volatile organic compound blend from human blood that attract mosquitoes. Although HMBPP has qualities needed for the development of novel attractant blend to mosquito for mass trapping, its attractiveness to wild African malaria vectors remain unclear.

The findings of this project will increase our understanding of malaria parasite transmission, and contribute to the development of novel tools for attracting, trapping and killing malaria vectors to reduce transmission of disease in endemic settings.

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