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Last Updated: 02/12/2024
Biomarkers, immune response and mechanisms associated with protection or morbidity in protozoan infections: Leishmania, Plasmodium, Trypanosoma cruzi and Toxoplasma gondii
Objectives
This is an “umbrella” project that houses sub-projects with the objectives of:
- Identify morbidity biomarkers in malaria caused by Plasmodium vivax: inflammatory mediators and miRNA;
- Study the immune response and mechanisms associated with protection and morbidity in Plasmodium infections in populations exposed to malaria;
- Identify and carry out the immunological characterization of B and T cell epitopes in Plasmodium sp. and its implications in vaccine processes;
- Identify modulators in the immune response in Chagas disease and Leishmaniasis;
- Study the role of CD4-CD8- T cells in Chagas disease
- Study of the role of extracellular networks of T lymphocytes (LETs) and “tissue resident macrophages” in leishmaniasis;
- Study the immune response in toxoplasmosis.
Principal Institution
Principal Investigators / Focal Persons
External reference
Thematic Categories
Date
Jan 2021
Funding Details
Coordination for the Improvement of Higher Education Personnel (CAPES), Brazil
Grant number: 696269
Project Site
Related Resources
