Last Updated: 05/08/2024
Application of field-deployable surveillance tool to enhance molecular xenomonitoring of multiple vector borne diseases
Objectives
The main objective of this project is to detect DNA from malaria and leishmania parasites in vectors using newly developed multiplex Lateral-Flow Recombinase-Polymerase-Amplification assays. The project will extend the assays to capture additional pathogens, including RNA viruses, and enable the delivery of a field-ready approach for multivector-borne disease surveillance.
London School of Hygiene and Tropical Medicine (LSHTM), United Kingdom
Molecular xenomonitoring (MX) is a disease surveillance method that involves the detection of pathogens in vector populations, which can be used as a proxy for human/animal infections. MX has been successfully applied to monitor lymphatic filariasis in elimination stages. However, MX is dependent on the use of polymerase-chainreaction methods, which need expensive instruments and are not field-deployable.
Jun 2023 — May 2024
$57,957
