Guidelines for compliance monitoring and inspection of activities involving genetically modified mosquitoes

This document is meant to serve as a guideline on Compliance Monitoring and Inspection (CMI) for biosafety regulators at institutional and national levels, as well as any personnel involved in managing and implementing the use of Genetically Modified Mosquitoes (GMM) in health. The guidance does not cover other GMMs in use outside the health sector, which are meant to ensure safety as per the applicable statutory provisions of a given country. The guideline applies to CMI duties of GMM activities under different phases of development, ranging from laboratory to cage population, as well as confined field trials and field-scale deployment. It aims to provide a regional framework to standardise and implement CMI of a GMM activity in Africa to ensure safety.