Last Updated: 30/01/2025
Defying nuclear conventions: How molecular innovations drive divergent mechanisms of chromosome segregation in parasitic eukaryotes
Objectives
This research investigates the rapid evolution of chromosome segregation mechanisms in malaria parasites, revealing that despite significant divergence, their cell division components share similarities with those in other eukaryotes. By identifying specific molecular innovations in these systems, the study aims to uncover potential new therapeutic targets for treating malaria.
Equal distribution of chromosomes during cell division is essential for propagation of life. In unicellular parasites this process evolved remarkably rapidly, resulting in unconventional ways of chromosome segregation. This research aims to pinpoint molecular innovations within these systems in relatives of malaria parasites, hoping to uncover opportunities for new therapies.
May 2021 — May 2024
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