Immune responses to asymptomatic malaria: dissecting cellular signatures to overcome immunosuppression and improve vaccination strategies

Objectives

This project will undertake a comprehensive immunological and molecular analysis of individuals experiencing asymptomatic malaria in an endemic area of Indonesia.

Principal Institution

Monash University (MON), Australia

Principal Investigators / Focal Persons

Diana Hansen

Rationale and Abstract

The project will demonstrate that asymptomatic malaria is not benign as previously thought, providing a framework for new polices supporting mass-screening and treatment of asymptomatic malaria. This project will also identify critical immune responses to eradicate these persistent infections with innovative vaccination strategies.

External reference

Project details

Thematic Categories

Asymptomatic Reservoir
Vaccines (Immune Correlates)

Date

Jan 2024 — Dec 2026

Total Project Funding

$589,951

Funding Details

National Health and Medical Research Council (NHMRC) Australia, Australia

Grant ID: 2028898

AUD 873,271