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Last Updated: 02/08/2024
Study of new antimalarial transdermal-drug development
Objectives
*Original title and text were machine translated from Japanese.
By combining selected existing antimalarial drugs with N-89 as a transdermal formulation, this study aims to ultimately optimize a transdermal N-89 combination drug that is sustained release and does not exhibit a first-pass liver effect.
Focusing on a transdermal formulation as a new dosage form that can be easily administered to children infected with malaria, the development policy was modified to create a transdermal formulation of N-89, which had already been discovered as a new oral antimalarial drug. Optimization was performed. For clinical use, partner drugs are added to the N-89 formulation, which is made from a base mixture of two types of amphipathic molecules with different molecular weights, Polyethylene Glycol (PEG), which are existing antimalarial drugs with different blood half-lives and structures. Selected from.
Apr 2023 — Mar 2026
$34,916
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