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Last Updated: 02/08/2024
Research aimed at developing cerebral malaria prevention and treatment methods targeting intestinal bacteria
Objectives
*Original title and text were machine translated from Japanese.
The purpose of this study is to clarify the pathogenesis of cerebral malaria in order to develop preventive and therapeutic methods for cerebral malaria that target intestinal bacteria.
The pathogenesis and protective immunity of malaria was examined from a completely new angle, that is, the involvement of intestinal bacteria, and discovered that the intestinal flora is involved in the pathogenesis of cerebral malaria in mice infected with the murine malaria parasite. Work has been ongoing to elucidate its detailed mechanism of action. The results of this research will provide new knowledge to conventional research on host-malarial parasite interactions, contributing to further understanding and rapid development, and will also contribute to the development of new malaria prevention and treatment methods as new malaria countermeasures.
Apr 2023 — Mar 2026
$34,916