Last Updated: 30/07/2024

Epitope-directed monoclonal antibody production for mosquito immune cells (for malaria)

Objectives

Luna Labs proposes to develop monoclonal antibodies (mAbs) for use in the identification and characterization of mosquito immune cells for immune responses and validation through various immunoassays and surface plasmon resonance (SRP).

Principal Institution

Luna Labs, United States

Principal Investigators / Focal Persons

Yang Yu

Rationale and Abstract

The project focuses on target proteins expressed in mosquito hemocytes that mediate innate cellular and humoral immunity to pathogens, and the antibodies produced will promote the research on human vector-borne diseases transmitted by mosquitoes.

Thematic Categories

Vaccines (Immune Correlates)

Date

Sep 2023 — Aug 2025

Total Project Funding

$599,993

Project Site

United States

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