Last Updated: 04/07/2024
Screening for transmission blocking drugs
Objectives
This project aims to develop novel antimalarial compounds targeting gametocytes, the sexual stages of the Plasmodium falciparum parasite responsible for severe human malaria.
Principal Institution
London School of Hygiene and Tropical Medicine (LSHTM), United Kingdom
Principal Investigators / Focal Persons
Rationale and Abstract
This initiative focuses on screening new antimalarial compounds for “transmission-blocking” activity, crucial for interrupting the cycle of infection and aiding malaria elimination efforts.
Utilizing a groundbreaking high throughput screening assay, the lab can evaluate the effectiveness of antimalarial drugs on both male and female gametocytes simultaneously, a vital step as each sex responds differently to treatment.
Thematic Categories
Date
Jan 2022 — Dec 2022
Total Project Funding
$130,000
Funding Details
Project Site
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