Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Warning: Undefined array key "file" in /var/www/vhosts/gestortectic.com/mesa.gestortectic.com/wp-content/plugins/fulltext-search/includes/wpfts_querylog.php on line 520

Last Updated: 14/05/2024

Medicinal chemistry progression of hits identified from the MMV pathogen box for malaria and tuberculosis

Objectives

This project seeks to continue medicinal chemistry efforts on a chemical class identified from the medicines for malaria venture (MMV) Pathogen box to develop an early lead with in vivo antitubercular/antimalarial activity as a proof-of-concept.

Principal Institution

University of Ghana (UG), Ghana

Principal Investigators / Focal Persons

Richard Amewu

Rationale and Abstract

The emergence of drug resistance has rendered most clinically used drugs ineffective. There is, therefore, the need to discover new, safe, effective and novel chemo types with new modes of action. This project seeks to continue medicinal chemistry efforts on a chemical class identified from the MMV Pathogen box to develop an early lead with in vivo antitubercular/antimalarial activity as a proof-of-concept

Date

May 2019

Funding Details
Bill and Melinda Gates Foundation (BMGF), United States

Grand Challenges Africa. Grand Challenges Africa: Drug Discovery
Project Site

Ghana

SHARE
SHARE