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Last Updated: 26/02/2024

Evaluating the feasibility and impact of larval source management in aquatic agriculture in regions with high malaria burden in Madagascar

Objectives

The objectives of this project is to evaluate the cost, logistics, and CEA feasibility of LSM in Madagascar.

Furthermore, answers to these questions will be provided by the results from the feasibility of LSM and impact on malaria morbidity.

  1. Does complementary LSM of aquatic habitats/rice paddies in combination with pyrethroid only ITNs provide additional control of malaria vectors in Madagascar by reducing larval and adult densities, indoor and outdoor human biting rates, sporozoite rate and the entomological inoculation rate (EIR)?
  2. Does complementary LSM reduce malaria transmission as indicated in HMIS data? Answers to these questions will be provided by the results from the study below to assess feasibility of LSM and impact on malaria morbidity.
Rationale and Abstract

To evaluate the feasibility  of  larval source management (LSM) as a complementary vector control tool to ITNs in Madagascar.  By using Bti (Bacillus thuringiensis israelensis) on vector populations and malaria incidence in high burden malaria districts in western and central Madagascar (Atsimo-Andrefana and Analamanga Regions) where rice irrigation fields are common larval habitats   and the surface area of water to cover with larvicide is quantifiable and <1km2. Atsimo-Andrefana and Analamanga are high malaria burden regions of Madagascar which were selected for this feasibility assessment for several reasons. In these areas, Arisco et al. 2020 and NMCP found the presence of Anopheles larvae to be associated with an individual’s increased odds of having malaria. The authors describe a quantifiable number of available larval habitats, each <1km2, the majority within 1km of human communities and positive for An. gambiae s.l. larvae. Further, the rainy season in the region is short (~ 3 months) which is ideal for LSM application and management.

Thematic Categories

Vector Control

Date

Jan 2021 — Jan 2023

Project Site

Madagascar

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