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Last Updated: 18/06/2024

Search for next-generation malaria vaccine

Objectives

The project will conduct a head-to-head infection prevention test to directly compare the vaccine efficacy with the previous vaccine using a mouse model. Next, i) safety test, ii) immunogenicity test, and iii) vaccine efficacy will be conducted as efficacy tests in monkey models.

Principal Institution

Kanazawa University, Japan

Principal Investigators / Focal Persons

Eihito Yoshida

Rationale and Abstract

Towards licensing out, the following pharmacological studies will be conducted. As an activity for out-licensing, a prototype vaccine that leads to out-licensing activities will be used at a parasitology conference held by inviting the person in charge of malaria vaccine development support from PATH and Wellcome Trust. To confirm efficacy pharmacological test and propagation inhibition effect by mouse experiment. To confirm the efficacy of protection against infection in an evaluation of protection against infection by a mouse experiment using a prototype vaccine. Conduct the selection of vaccine specifications.

Thematic Categories

Vaccines (Immune Correlates)

Date

Apr 2020 — Mar 2023

Total Project Funding

$186,750

Funding Details
Project Site

Japan

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