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Last Updated: 18/06/2024
The role of resident and circulating CD8 T cell memory in the control of liver infections
Objectives
To investigate how CD8+ T cells and other T cells recognise and destroy pathogens like malaria that infect liver cells, without damaging the remaining liver tissue, with the aim of designing better vaccines against liver infections.
Principal Institution
Principal Investigators / Focal Persons
Rationale and Abstract
CD8+ tissue-resident memory T (Trm) cells are a specialized population of immune cells that act as front-line defenders against pathogens in organs such as the liver.
Thematic Categories
Date
Nov 2021
Total Project Funding
$691,261
Funding Details
National Health and Medical Research Council (NHMRC) Australia, Australia
Grant ID: 2012701
AUD 920,958
Project Site