P. falciparum Community Project

Community project goals:

• Enable malaria researchers to analyse genome variation in the parasite samples that they collect: Advances in sequencing technology have made it possible to analyse parasite genome variation in samples collected during clinical and epidemiological studies of malaria but relatively few groups have the statistical and computational resources needed to deal with raw sequence data.  To address this need, MalariaGEN has established a sequence data analysis pipeline that enables researchers who have collected parasite samples to generate sequence read data and translate this data into standardised  genotype calls that are suitable for epidemiological and population genetic studies, e.g. of drug resistance or antigenic variation.
• Provide the malaria research community with a collaborative framework to investigate common forms of genetic variation in P. falciparum: Data on the natural diversity of P. falciparum in different geographical regions is crucial for many aspects of malaria biology and disease control. This depends on clinical and epidemiological studies that often require a long‐term investment to achieve their scientific objectives.  The Community Project enables different research groups to share and release data on parasite polymorphism without compromising their ability to analyse and publish their own findings. Working together in this way, the Community Project is creating an integrated, global view of parasite diversity that can help underpin malaria research and control efforts.

Project details

Genetics and Genomics
Surveillance

Jan 2010 — Dec 2022

Bangladesh
Benin
Burkina Faso
Cambodia
Cameroon
Colombia
Côte d'Ivoire
Dem. Rep. of Congo
Ethiopia
Ghana
Guinea
Indonesia
Kenya
Lao PDR
Madagascar
Malawi
Mali
Mauritania
Myanmar
Nigeria
Papua New Guinea
Peru
Senegal
Tanzania
Thailand
The Gambia
Uganda
Vietnam

Resource Centre for Genomics

Genetic Epidemiology