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Last Updated: 30/06/2024
A vaccine based on a newly-discovered antibody in men that prevents malaria infection in the placenta
Objectives
The goal was to identify the antigens from the P. vivax that generate functional antibodies against P. falciparum.
Principal Institution
Principal Investigators / Focal Persons
Rationale and Abstract
Colombian men exposed to malaria are found to have antibodies that can prevent infection in the placenta of a pregnant woman. This University of Alberta finding forms the basis for developing a novel vaccine against several forms of malaria, which cause 10,000 maternal deaths and 200,000 stillbirths annually. The researchers discovered that men exposed to malaria have antibodies that can prevent infection in the placenta. This unexpected finding forms the basis of a novel approach to a vaccine that protects pregnant women exposed to multiple species of malaria.
Thematic Categories
Date
Oct 2013 — Mar 2015
Funding Details
Related Resources
