Managing insecticide resistance in Burkina Faso and Côte d’Ivoire (REACT): researches on new vector control strategies

Objectives

The objectives of this project are:

To perform a Phase III randomized controlled trial of new vector control tools in combination with Long Lasting Insecticidal Nets (LLINs). The study will evaluate the benefit to use 1) insecticidal paints, 2) larvicides, 3) Ivermectin for both human and domestic animals and 4) a strengthened information, education and communication strategy to complement the universal coverage with LLINs through a cluster randomized trial.
To assess the efficacy of each combination against malaria transmission, prevalence, and incidence.
To assess the efficacy of each combination to manage insecticide resistance.
To characterize the residual transmission and to assess its determinants.
To study the behaviour of old, infectious and resistant Anopheles.

Principal Institution

Principal Investigators / Focal Persons

Partner Institutions

Study Design

Outcome measures:

ClinicalTrials.gov Identifier: NCT03074435

Study Type :	Interventional (Clinical Trial)
Allocation:	Randomized
Intervention Model:	Parallel Assignment
Masking:	None (Open Label)
Primary Purpose:	Prevention