Last Updated: 01/10/2025
Elucidation of the molecular mechanism of oocyst formation and differentiation of malaria parasites: Searching for wall-constituting proteins
Objectives
This research aims to elucidate the molecular mechanisms of formation and differentiation of the oocyst stage, the period when vector mosquitoes and malaria parasites interact, and will lead to the creation of new control strategies that target the oocyst formation stage.
Obihiro University of Agriculture and Veterinary Medicine, Japan
Various strategies for the control of malaria have been implemented, but no effective method has been established to date, and the creation of new strategies is a challenge. Malaria parasites are transmitted by Anopheles mosquitoes, so in the natural world, the survival of the parasites and the spread of the disease depend on the vector’s ability to transmit the disease. Malaria parasites taken in by mosquitoes through blood feeding form oocysts to multiply within the mosquito’s body, but the number of parasites is greatly reduced due to selection pressures such as the mosquito’s immune response.
Apr 2024 — Mar 2029
$121,894
Related Resources
