Comprehensive functional analysis of novel molecules localized in secretory vesicles of malaria parasite male gametocytes

Objectives

The main aim of this study is to search for proteins adjacent to PyMiGS, a male-specific secretory vesicle molecule by using a proximity-dependent biotin labeling method , and identify a group of molecules localized in male secretory vesicles. Furthermore, this study also aim to elucidate the function of male secretory vesicles in sexual reproduction by creating and analyzing parasites lacking the relevant gene.